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Cocaine Vaccine Research
Up until now, the vaccine has been tested on rats and non-human primates. Biologically, non human primates are said to be closer to humans than rats. The success rate of the cocaine vaccine results has urged the researchers to test the vaccine on humans. The tests conducted on rats injected with the virus and cocaine showed less hyperactive behavior than those mice which were given just cocaine.
Researchers attempted to study the effectiveness of the cocaine vaccine in non-human primates by measuring the amount of cocaine attaching itself to the dopamine transporter. If cocaine reaches the brain it prevents the transporter from carrying dopamine out and attaches itself to the dopamine transporter. This keeps the neurotransmitter active in producing a drug high.
An isotope was attached to the dopamine transporter to measure the amount of tracer attaching to the dopamine receptor in presence or absence of cocaine. The activity of the tracer was seen using a Positron Emission Tomography (PET). There was no change in tracer activity in vaccinated and non- vaccinated primates when cocaine was not given. There was a significant drop in activity of tracer when cocaine was given, in non-vaccinated animals.
This means that in the absence of vaccine, cocaine attaches itself to the dopamine receptor by replacing the tracer. The cocaine occupancy of the dopamine receptor in vaccinated primates was reduced to 20% by use of the vaccine. Previous researches have shown that to produce high cocaine should occupy 47% of the dopamine transporter.
The vaccine was further reported to have lasted 13 weeks in rats and 7 weeks in non-human primates. Researches do not know the amount of vaccine shots that would be required for humans to make it effective. With preliminary results being so satisfying, conducting human trials in near future for the cocaine vaccine gives hope to the cocaine addicts in Saint Paul who want to desperately stop using.
Cocaine Vaccine: Methods to Treat Cocaine Addiction in Saint Paul
Thousands of people in Saint Paul suffer from cocaine addiction, and this has serious consequences as far as healthcare expenses and fatalities are concerned. There are several treatments for cocaine addiction in Saint Paul. As far as medications are concerned, methadone works well with heroin addiction, but unfortunately, there is no such alternative for cocaine addiction.
That is why recently scientists have been working on developing a cocaine vaccine. Like methadone, a cocaine vaccine may be able to prevent the pleasurable sensations associated with the addictive.
Drug Addiction Treatment
Treating drug addictions should be the first priority for anyone who has been hooked on drugs, be it any kind. There are a lot of treatment facilities around, especially in Saint Paul which offer a variety of drug addiction rehabs. Seeking treatment as soon as any symptoms are present is the best possible way to overcome the difficulties that come with addiction.
Addicts should always seek help as soon as they suspect that they have a problem. Without help, they will not get far because they will either continue using or continue to relapse. The best advice is to seek help from a drug addiction specialist in Saint Paul .
At Saint Paul Drug Rehab, we genuinely care about each participant's well being. Our patient staff is dedicated to helping each person who needs our help to attend to all of the necessary details that can help ensure treatment as quickly as possible. We understand the urgency of making every moment count, and do our best to make sure the process is as seamless as possible.
Currently tests for the meth vaccine are being run on rats since their biological make up is similar to that of humans. Results of the test showed that the M6 was effective in blocking out two effects of the methamphetamine drug. The first was the lack of regulation in body temperature and the other was the increase in physical activity.
This means that addicts in Saint Paul will regain control of their body temperature by use of the meth vaccine. This in turn will reduce the risk of stroke or cardiac arrest.
The decrease in physical activity would cause the meth high to be diminished which will reduce the incentive to use the recreational drug.
So far, the meth vaccine has been effective in reducing the harmful effects of the drug. The vaccine also reduces the highs that meth produces. The next step is to test this vaccination on human subjects.
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